Hemophagocytic lymphohistiocytosis (HLH) is a rare, potentially fatal syndrome characterized by unchecked and persistent activation of cytotoxic T-cells and natural killer (NK) cells (Al-Samkari, Berliner, 2018). This uncontrolled immune response leads to increased secretion of inflammatory ...
Chimeric antigen receptor T (CAR-T) therapies have resulted in durable remissions for patients with refractory hematologic malignancies; however, patients can experience many side effects following administration. Cytokine release syndrome (CRS) occurs as a result of rapid immune activation induced ...
Background and History Biological products or biologics are typically large, complex molecules made within a living system, such as an animal cell. Biologics are used to diagnose, prevent, treat, and cure diseases or medical conditions. Examples of biologics include therapeutic proteins like ...
Elizabeth S. Waxman, BSN, RN, MSN, ANP-BC
Read more
Abigail Shockley, PharmD
Justin Musco